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and the IC50 value of the compound against CaM-KII is 10 μg/mL
CAS Number: 2381320-35-8
Rat hepatocarcinoma cells (FAO) stimulated by fetal calf serum (FCS) exhibits a significant proportion in S phase (32
Chemical Name: N-[5-[2-(2
but increases the climbing time (F2
Bedaquiline Catalog No.:M8161-2 and the IC50 value ofBedaquiline, also known as TMC207 and R207910, is a diarylquinoline anti tuberculosis drug, which was discovered by a team led by Koen Andries at Janssen Pharmaceutica. Bedaquiline blocks the proton pump for ATP synthase of mycobacteria. ATP production is required for cellular energy production and its loss leads to cell death, even in dormant or nonreplicating mycobacteria. It is the first member of a new class of drugs called the diarylquinolines.