Pay in 4 interest-free payments of $20.00 Learn more
Ships within 48 hours · Estimated delivery Oct 12 - Oct 17
Maintaining the methoxy/fluoro arrangement at C-2′/C-5′ and varying aminoalkyl R1 substitution resultes in single-digit nanomolar LRRK2 cellular activities for GNE-7915 and compound 19
which is predominantly cleared renally
InChi: InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23
Haematologica
InChiKey: BGIYKDUASORTBB-UHFFFAOYSA-N
Vinblastine sulfate Size:Solid 2 mg Maintaining the methoxy/fluoro arrangement atVinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin dependent Ca++ transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
US$ 12.00
US$ 15.00
US$ 30.00