ARP 101 Catalog No.:M23013-C Smiles: FC(F)(F)C1C=C(N=C2C=1C=CC1=NC(=CN12)C1=NN=CO1)C(F)(F)F

Smiles: FC(F)(F)C1C=C(N=C2C=1C=CC1=NC(=CN12)C1=NN=CO1)C(F)(F)F

is a novel dual PI3K/mTOR inhibitor with an IC50 ~1 nM

MPEP reverses maze learning and PSD-95 deficits in Fmr1 knock-out mice

4)20-29(71)28-10-11-36-68(7)14-13-37(67(5

Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM

ARP 101 Catalog No.:M23013-C Smiles: FC(F)(F)C1C=C(N=C2C=1C=CC1=NC(=CN12)C1=NN=CO1)C(F)(F)FARP 101 is a selective MMP 2 inhibitor with IC50 value of 0. 81nM. MMP 2 is an enzyme and involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis . ARP 101 shows inhibition of fibrosarcoma HT1080 cell growth in vitro. ARP 101 has shown ~250 fold selectivity of MMP 2 over MMP 1 and ~100 fold