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Chemical Name: 4-(5-(4-methoxyphenyl)-3-phenyl-4
Solubility: Water: 29 mg/mL(194
CAS Number: 2166599-74-0
but not to vascular smooth muscle and endothelial cells
InChi: InChI=1S/C12H7Cl2NO3S2/c1-6(16)10-5-8(15(17)18)12(20-10)19-9-4-2-3-7(13)11(9)14/h2-5H
DuP-697 rphostin A9 Chemical Name: 4-(5-(4-methoxyphenyl)-3-phenyl-4DuP 697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX 2 inhibitor (IC50 of 10 nM and 800 nM for human COX 2 and COX 1, respectively). DuP 697 exerts antiproliferative (IC50 of 42. 8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP 697 inhibits prostaglandin synthesis and has anti inflammatory, anticancer and antipyretic effects. Product information CAS Number:
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