![AM095 (free acid) - CAS# 1228690-36-5 tate) Chemical Name: 3-ethyl-1-(4-{4-[(3S)-3-methylmorpholin-4-yl]-7-(pyrimidin-2-yl)-5H](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10154_1621561416.gif?v=1742883124)
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Chemical Name: 3-ethyl-1-(4-{4-[(3S)-3-methylmorpholin-4-yl]-7-(pyrimidin-2-yl)-5H
and disrupts the repair of dsDNA breaks probably through suppression of Rad51
cis-Diaminodichloroplatinum
CN1C2=CC=C(C=C2N=C1CCCC(O)=O)N(CCCl)CCCl
111(3):906-12
AM095 (free acid) - CAS# 1228690-36-5 tate) Chemical Name: 3-ethyl-1-(4-{4-[(3S)-3-methylmorpholin-4-yl]-7-(pyrimidin-2-yl)-5HAM095 is a potent LPA1 receptor antagonist because it inhibited GTPS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0. 98 and 0. 73 M, respectively, and exhibited no LPA1 agonism. Lysophosphatidic acid (LPA) is a bioactive phospholipid that signals through a family of at least six G protein coupled receptors designated LPA1 6. LPA type 1 receptor (LPA1) exhibits widespread
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