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Tipiracil Hydrochloride Catalog No.:M9551-10 Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2

SKU: 882020317

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Description

Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2

Smiles: CC1C=CC(=CC=1)C1=NN(C2=NC=NC(N)=C12)C(C)(C)C

All LGK974-sensitive pancreatic cancer cell lines carried inactivating mutations of RNF43

Formula: C18H24O3

with IC50 values between 30 mM and 100 mM in vitro cellular and enzymatic assays

Tipiracil Hydrochloride Catalog No.:M9551-10 Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS 102, which is an anticancer drug candidate currently in clinical trials. TAS 102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down

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