Pay in 4 interest-free payments of $7.25 Learn more
Ships within 48 hours · Estimated delivery Jul 29 - Aug 3
12(24):2727-40
pii: S1567-5769(15)30138-7
Carmody LC
and safe mGlu5 inhibitor with good oral bioavailability and long half-life supportive of once-daily administration
It has >10-fold selectivity over DYRK3 and DYRK2 (IC50 ~800 nM and 900 nM respectively
TraMetinib - CAS# 871700-17-3 0201 12(24):2727-40Trametinib, also known as GSK1120212, CAS No. 871700 17 3, is a n orally bioavailable inhibitor of mitogen activated protein kinase kinase (MEK MAPK ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of growth factor mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual specificity threonine tyrosine kinases often upregulated in
US$ 52.00
US$ 68.00
US$ 114.99
US$ 52.00
US$ 52.00
US$ 50.00